Saturday, June 26, 2021

Indigenous People with a Lower Risk of Cognitive Decline

A recent article published in the Journal of Gerontology, Series A: Biological Sciences and Medical Sciences reports on an interesting study involving the indigenous Amazon people of Bolivian knowns as the Tsimane. A total of 746 Tsimane adults, ages 40 to 94, were recruited for the study by a team of international researchers. The published results show participants experienced less brain atrophy than their American and European counterparts. In fact researchers reported a 70% slower decrease in brain volume than that found in Western populations. Accelerated brain loss volume is one of the factors known to contribute to cognitive decline and to be a sign of dementia.

The Tsimane study group was transported to Trinidad, Bolivia for CT scans in a trip that sometimes took up to two days. Their scan results were then compared to three industrialized populations in European and America. Researchers say the Tsimane typically have no access to medical care but lead a very active lifestyle and consume a diet high in fiber consisting of vegetables, fish and lean meat. 


An unexpected result was discovering the Tsimane people had high levels of inflammation, which is typically associated with brain atrophy in Westerners. The study authors suggest “Tsimane's low cardiovascular risks may outweigh their infection-driven inflammatory risk, raising new questions about the causes of dementia.” They explain inflammation in Westerns is generally associated with obesity and metabolic causes fueled by diets high in sugars and saturated fats, while the Tsimane’s inflammation is most likely a result of infectious diseases, the leading cause of death.  


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Source: sciencedaily.com/releases/2021/05/210526185858.htm


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